Photodynamic Therapy (PDT)

If you are looking for a dermatologist in Rome specialized in photodynamic therapy (PDT), Medicalia, directed by Dr. Elisabetta Perosino, offers this treatment.

Conditions and issues treated

What is Photodynamic Therapy (PDT)?

Photodynamic therapy (PDT) is a non-invasive method that involves using a photosensitizing agent activated by a lamp emitting red light at a specific wavelength.

Through photophysical, photochemical, and photobiological phenomena, the combination of the applied substance and the light causes the death of cells that have accumulated the sensitizing drug. This is common in rapidly growing cells such as certain epithelial skin tumors, basal cell carcinomas, and actinic keratoses, or inflammatory conditions like acne and rosacea.

Purpose of PDT

Photodynamic therapy is generally used to treat certain types of neoplasms, and due to its oncological applications, it is also called photochemotherapy.

Additionally, it is used to treat inflammatory conditions like acne and rosacea or skin growths like warts.

PDT is also an excellent therapy against skin aging and hair loss, yielding great results, especially when combined with other treatments.

For the treatment of non-oncological conditions, red or blue light lamps can be used without the photosensitizing agent. This is known as photobiomodulation, where the lights directly stimulate the target organ, providing anti-inflammatory, plastic, or anti-wrinkle effects, depending on the need.

Looking for a dermatologist for photodynamic therapy in Rome?

How photodynamic therapy is performed

Photodynamic therapy (PDT) usually does not require anesthesia, except in certain cases (such as tumors or other conditions) and is performed as an outpatient procedure in multiple stages.

The doctor administers a photosensitizing agent intravenously.

Depending on the treatment, different substances may be used as agents.

After a period of time following the injection (usually one to three days), the patient returns to the clinic for the second phase of the treatment, where the specialist exposes the affected area to light of an appropriate wavelength.

This causes the photosensitizer to produce reactive oxygen species that kill the tumor cells. This process is called phototoxicity and typically takes from a few minutes to an hour.

A follow-up visit may be required a few days after the therapy to ensure that no residual tissue needs to be removed.

Complications and risks of photodynamic therapy

Medicalia in Rome is a dermatology center specialized in photodynamic therapy (PDT). Il direttore è la Dr. Elisabetta Perosino, specialista in Dermatologia e Membro del Consiglio direttivo ISPLAD.

For more information or to book an appointment, contact us.

Patient Disclaimer
The information on this page is for informational purposes only and cannot replace the advice of a physician.

Bibliography

Allison RR, Sibata CH. Photodynamic therapy: mechanism of action and role in the treatment of skin disease. G Ital Dermatol Venereol. 2010 Aug;145(4):491-507. PMID: 20823792.

Allison RR, Moghissi K. Photodynamic Therapy (PDT): PDT Mechanisms. Clin Endosc. 2013;46(1):24-29. doi:10.5946/ce.2013.46.1.24

Loading